Nevertheless they give essential additional information.
It is essential to generate additional data in larger studies in order to test the validity of this proteomic approach to preimplantation aneuploidy detection and to define the real sensitivity and specificity of this methodology.
Because of the central position occupied by Epac in the exocytotic cascade, we considered essential to gather additional data to validate its role in driving the two downstream pathways described before.
The results will be used firstly to provide additional data essential for monitoring the risk of overdose, abuse, dependence and misuse of these products, and to begin awareness-raising and to provide information for health care professionals, in order to significantly improve the management of sickle-cell disease-related pain.
Although the optical characteristics of solutions including tungsten bronze compounds have been previously analyzed [5], additional data are essential to fully understand the absorption and reflection-induced optical characteristics for the composite coating film application.
However, when a non-pairwise SAM method was used (i.e. two unmatched groups: (i) all baseline samples and (ii) all three-month samples), XPN correction of the integrated data was essential (Additional file 3B&C).
Several additional data are therefore essential: 1) More information on the expression patterns of the different players in the BMP pathway is essential: Where is dpp expressed?
At all postnatal visits, additional data on immediate essential newborn care practices (bathing, drying, wrapping, breastfeeding), reported morbidity, and vital status of the child were collected.
Several additional data are therefore essential: The reviewers have noted that a decreasing role of Toll signaling accompanied by an expanded function of BMP was already described in our recent CB paper on Nasonia.
Conditional/unclassified: A clinical event, including laboratory test abnormality, reported as an adverse reaction, about which more data are essential for a proper assessment or the additional data are undergoing examination.
