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Some CMV proteins are also related to antiviral mechanisms, including the viral DNA polymerase UL54 and UL97, which encodes a protein phosphotransferase enzyme that phosphorylates the antiviral drug ganciclovir, an essential activation step required for its inhibitory effect on CMV DNA replication [20 22].
Effector binding is central to a number of essential activation processes and provides essential information on interactions involved therein.
Even if not essential, activation of Jak/Stat3 appears to be limiting for induction of pluripotency.
After cellular uptake, the first essential activation step is catalysed by hypoxanthine-guanine phosphoribosyl transferase (HPRT).
For the Ffh-FtsY heterodimer the essential activation function of the 3'OH is mediated in trans [ 20].
The simulation of changes in isotopomer distribution induced by low doses of edelfosine revealed essential activation of the TCA cycle (including anaplerosis).
Similar(53)
Rad26 is essential for activation of Rad3, which is required for both Cds1 and Chk1 activities [38], [39].
A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex.
The muscle-specific protein phosphatase PP1G/R GL)(G(M is essential for activation of glycogen synthase by exercise.
This is essential for activation of DOUBLE TOP and specification of floral identity.
Thus, the minimal set of proteins essential for activation and catalysis remains elusive.
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