Sentence examples for especially substantial when from inspiring English sources

The difference in cost is especially substantial when sequencing a large genome.

Stability issue has a significant role in the design of structures; especially it becomes even much more substantial when the design deals with the thin-walled structures under complex loading condition, which is a combination of two or more loading types at the same time.

Level of civil unrest was substantial when this study was carried out, especially in Ghazni.

"Labeling a work a forgery is an extreme step," Luke Nikas, one of Ms. Freedman's lawyers, said in an interview, "especially when substantial evidence of authenticity exists.

This gain in efficiency can be substantial especially when there are patients not complying with their assigned treatments.

Determination of temperature from optical emission spectra is an inverse problem that is often very difficult to solve, especially when substantial noise is present.

The added heft and weight make it feel like a much more comfortable handful than many current-day devices, which can tend to feel cheap or less than substantial, especially when they use plastic as their primary case material.

The bias could be substantial especially when data are sparse [ 23, 24].

This study has shown that opportunity costs of community-based health insurance may be substantial, especially when they rely on government health workers and district managers.

Testing fees can be substantial, especially when individual genetic variants are assayed sequentially, and indeed are soon likely to rival the cost of obtaining an entire genome sequence.

These estimates are also prone to random error, which can be substantial, especially when survival experience between small populations is compared.