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Post-transcriptional modifications at tRNA's wobble position 34, especially modifications of uridine 34, enable wobble to occur.
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It sometimes causes macroscopic or microscopic changes in the solid phase, especially modification of crystal type and size, specific surface changes or changing in chemical composition of solid phase, and it is commonly a slow process.
Much of this heightened interest derives from improved technologies that have enabled researchers to better address the role of macromolecular modification (especially protein modification) in sensing and mediating biological responses to reactive species.
But she added that other strategies — especially loan modifications like those recommended in the government's "Making Homes Affordable" program — are increasingly a first line of defense against foreclosure.
However, knowledge on the risk of these editing tools is insufficient especially when modifications are heritable.
The size, shape, and surface chemistry, especially hydrophobic modifications, exert significant impacts on the in vivo fate of RNA nanoparticles.
The results will benefit the design of band structures, especially subtle modifications by selecting suitable wall undulations.
As a result, the analysis of processes as a whole can be a promising approach to process intensification especially when modifications to one process unit affect other units.
Strictly applied, the criteria for ICHD diagnoses may be mutually exclusive, but this exclusivity tends to be lost with "probable" diagnoses and, especially, with modifications necessarily made to these criteria (see page 19).
Interestingly, the results show that even for a relatively short-span bridge, aeroelastic coupling between modes of vibration can occur due to the peculiar structural dynamic characteristics of the bridge especially during modifications, and this coupling must be considered.
In addition, DNA methylation is associated with other epigenetic alterations, especially histone modifications and RNAi pathways.
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