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High pressure especially alters many macromolecules while small molecules usually remain unchanged.
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Larrea invasion is thought to result from multiple drivers including overgrazing, altered disturbance regimes, elevated atmospheric CO2, and especially altered precipitation regimes and increased temperatures [28], [34].
In the most severe cases, defined by extraordinarily high lithium levels (>4.0 mmol/l) or marked clinical symptoms, especially altered consciousness, extracorporeal methods such as hemodialysis should be instituted.
Nicotine also significantly enhanced the regional efficiency of limbic and paralimbic areas of the brain, areas which are especially altered in diseases such as Alzheimer's disease and schizophrenia.
Even though the dramatic effect of some point mutations on IgE binding has been elucidated using Bet v1 as a model allergen [8], [9], nitration has been discussed to especially alter IgG epitopes [10].
Genes coding for components of multivesicular body formation were especially altered.
General symptoms, especially altered mental status and dyspnea, appear to be more common in severe sepsis than in milder infections.
Thus, the circuits needed to represent information in memory stores and to provide guidance for actions are especially altered in schizophrenia (Fig. 9).
Hormonal changes, especially altered E2 status, may therefore be a relevant factor for bone loss and osteoporosis in male patients with inflammatory bowel disease (IBD).
Improper management of metabolic disturbances especially altered lipid and protein metabolism in diabetes results in grave cardiovascular complications which causes increasing diabetes-related mortalities [ 1].
Epigenetic modifications (especially altered DNA methylation) resulting in altered gene expression may be one reason for development failure or abnormalities in cloned animals, but the underlying mechanism of the abnormal phenotype in cloned piglets remains unknown.
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