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Such feature is critically important for the virus to adapt to environmental changes by escaping the host immune system and by escaping candidate vaccine.
Blood stage parasites are known to extensively remodel erythrocytes [4], [5] to create an environment conducive to nutrient acquisition, escaping the host immune system, and for replication.
The evolution of bacterial organelles involved in host-pathogen interactions is subject to intense and competing selective pressures due to the need to maintain function while escaping the host immune response.
Its role in escaping the host immune system and cytotoxic activity is well known.
In some species, the structural diversity of the cap protein has been reported to be a mean of escaping the host immune system [ 95].
Recombination allows the virus to increase its genetic fitness, to evolve, and to spread in the host population by escaping the host immune response [ 5].
Similar(45)
How do Leptospira interrogans escape the host defenses?
However, pathogenic microbes also control and escape the host complement and immune attack.
The remarkable capacity of this pathogen to escape the host immune system for decades and then to cause active tuberculosis disease, makes M.tb a successful pathogen.
This article discusses antigenic variation; the different mechanisms used by viruses to escape the host immune system and the resulting problems with vaccine design and/or production.
Indoleamine 2,3-dioxygenase 1 (isO1) is frequently hijacked by tumors to escape the host immune response, and the enzyme is now firmly established as an attractive target for cancer immunotherapy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com