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How do Leptospira interrogans escape the host defenses?
However, pathogenic microbes also control and escape the host complement and immune attack.
This article discusses antigenic variation; the different mechanisms used by viruses to escape the host immune system and the resulting problems with vaccine design and/or production.
Indoleamine 2,3-dioxygenase 1 (isO1) is frequently hijacked by tumors to escape the host immune response, and the enzyme is now firmly established as an attractive target for cancer immunotherapy.
The remarkable capacity of this pathogen to escape the host immune system for decades and then to cause active tuberculosis disease, makes M.tb a successful pathogen.
This RNA thermometer is now thought to encourage entry to a lytic cycle under heat stress in order for the bacteriophage to rapidly replicate and escape the host cell.
This variability allows AAV to escape the host immune responses and to adapt to different receptors.
To achieve the burst of lymphocyte proliferation which initially establishes the latent pool, gammaherpesviruses have to escape the host immune control [47].
As individual ticks do not express the same range of anticomplement proteins, certain individuals in a population would be able to escape the host immune reaction.
This switch between the haemoglobin receptors may be a means to escape the host defences because of the presence in the patient blood of antibodies directed against HmbR.
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Such feature is critically important for the virus to adapt to environmental changes by escaping the host immune system and by escaping candidate vaccine.
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