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Fast-evolving parasites may adapt to the most common host genotype and escape presentation of their antigens to the adaptive immune system of the host [ 48].
The existence of XCI in females offers a potential mechanism where by X-linked self-antigens may escape presentation in the thymus or in other peripheral sites that are involved in tolerance induction [ 9, 10].
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Furthermore, we have only studied the adaptation of HIV-1 to escape antigen presentation by means of amino acid substitutions.
HIV-1 viruses are highly capable of mutating their proteins to escape the presentation of CTL epitopes in their current host.
In fact, P31 49, unlike P57 67, bypassing HLA-DR-positive late vesicles and escaping antigen presentation at the basolateral membrane cannot stimulate gluten-sensitive T cells [11], preventing oral tolerance.
Our results demonstrate significantly more efficient lysosomal escape and cross-presentation of antigen from dendritic cells (DCs) that were exposed to "both" and "in" nanoparticles.
Parasites use mechanisms like inhibition of antigen presentation to escape immune response, however, a high growth rate induces massive macrophage recruitment [ 13].
In this paper we show that the distribution of predicted CTL epitopes in HIV-1 appears to be random, and is similar to the distribution of CTL epitopes in organisms that are not under selection pressure to escape the human antigen presentation pathway.
Schilowitz has invited me to a Cinemark XD theater in Los Angeles to view his latest bid for cinematic possibility: Barco Escape, a three-screen panoramic presentation designed for a new kind of audience engagement.
The aversive learning paradigm has been used extensively in our laboratory for the last 20 years; it is based on the crab's escape response elicited by the presentation of a visual danger stimulus (VDS), which represents the negative reinforcement [14].
Thus, low-dose IFN- γ secreted by the latter cells locally injected at the tumour resection site (where a few tumour cells may escape surgical intervention) may promote presentation of peptide-derived tumour-associated antigen to T lymphocytes leading to specific anti NB responses.
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