Sentence examples for escalation schemes from inspiring English sources

As it was anticipated that myelotoxicity might be dose limiting even at dose level 1a, further (lower) dose escalation schemes were devised.

In the first cohort only, a dose escalation scheme was applied where study drug was not escalated to the next dose level unless the safety and tolerability of the previous doses were acceptable by sponsor and clinical team.

Interestingly, when calcitriol treatment was discontinued after the escalation scheme this sensitization benefit was lost.

Additionally, we also investigated the "long-term" calcitriol cryosensitization potential using an in vitro dose escalation scheme.

Additionally, maintenance of 80 nM calcitriol for 20 days after the escalation scheme resulted in complete cell death at the −25 °C isotherm with no re-growth after 3 days.

The dose escalation followed a conventional dose escalation scheme.

The dose escalation scheme is summarised in Table 1.

The dose escalation scheme is described in box 1.

The dose escalation scheme is outlined in Table 1.

A pharmacokinetically guided dose escalation scheme was used, for several reasons.

The dose escalation scheme could, however, be modified if considered appropriate based on acquired clinical and pharmacokinetic data.