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They could afford to pay for faster access, but that doesn't mean they want to spend their money on it — especially if it could lead to an escalation, over time, of the Internet providers' fees.
Still, some experienced dose escalation over time, and risk factors were previous use of other psychotropic drugs, long time use, choice of first-time drug and prescriber's specialty.
Further, while this analysis focused on daily usage over the entire study period, it would be interesting to observe trends in dose escalation over time for drugs in the GLP-1 receptor agonist class.
Adalimumab is recommended for patients with Crohn's disease not responding to or unable to tolerate infliximab[ 14] due to its potential advantages over infliximab in terms of elimination of infusion reactions and possible reduction in the requirement for dose escalation over time [ 15].
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However, the doses prescribed were rather low and we did not see any evidence of a major dose escalations over time.
We did not see any signs from registry-data of major dose escalations over time among patients who received prescriptions for potent opioid analgesics after tibial shaft fractures.
We did not see any signs in registry-data of major dose escalations over time in patients on potent opioids after tibial shaft fractures.
For all comparisons (figure 2A H) we found the differences in risk of dose escalation increasing over time.
24 The risk of dose escalation increased over time, but only 749 (0.9%) ended up as excessive users.
"People change over time.
We did not account for changes or escalation of therapy over time in the model for those with GCK-MODY or true type 2 diabetes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com