Being coerced into assuming a worst-case scenario can only lead to an escalation of life-shattering false allegations.
After Doggystyle, rappers felt increasingly compelled to walk it like they talked it, with this escalation of real-life gangsta posturing culminating in the murders of Tupac Shakur and Biggie Smalls.
Some of that is due to reforms, including use-of-force policies that stress the importance of de-escalation and the sanctity of life.
The secondary objectives are to determine the effect of dose escalation on overall survival, progression free survival, quality of life and rate of grade 3-5 toxicities.
The apparent treatment "failure" caused by non-adherence can lead to unnecessary treatment escalation resulting in increased costs and decreased quality of life [ 6- 8].
The goals of the pharmacological anti-migraine preventive therapies include reduction of migraine attack frequency, intensity, duration and disability; improvement of health-related quality of life and avoiding of migraine attacks escalation and medication misuse [14].
Most infants tolerated escalation in IL to 3 gm/kg/day by day 4 of life.
But they also say they are accustomed to the periodic escalations in tensions, which they describe as just another part of life on this disputed island.
Expert evidence was heard, from James Hansen, the former head of Nasa's Goddard Institute, on the immediacy of the threat to life caused by escalation of emissions, to MPs who confirmed government inertia.
The continuous escalation of the technical means of advanced life support associated to the antibacterial and antifungal therapy required by the proven or presumed etiology.
We also had a systematic dose escalation protocol and included secondary outcomes such as behavioural function and quality of life measures.
