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With attention to these two key variables, and to how they change over the course of a sanctions regime, policy makers can pinpoint when diplomatic intervention is likely to succeed or when escalation is necessary.
For patients in extremis from massive PE, emergent treatment escalation is necessary in the form of systemic thrombolysis, CDT, or combination therapy depending on the circumstance.
The first one, "risk of escalation" clustered items related to the fact that once a morphine treatment is initiated, a dose escalation is necessary with potential deleterious effects on life expectancy.
Whether such tamoxifen dose escalation is necessary to increase tamoxifen efficacy in PMs and IMs and whether it is safe in view of long-term toxic effects is unknown and needs to be further explored.
We have been performing conventional irradiation for postoperative local recurrent lesions with a total dose of 60 Gy (2 Gy/fraction · 5 fractions/week), but we have considered that dose escalation is necessary to cure patients because rectal cancer has many hypoxic fractions [ 11].
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In England, those in favour of the air strikes, 54 per cent, back the line that an escalation of military action is necessary to prevent Isis terrorists becoming stronger in the Middle East and beyond.
The authors argue that with the huge volume and the accelerating escalation of information, it is necessary for learners to have a tool that supports them to access and process information.
Thus, to be able to evaluate at least eight patients after dose escalation, it was necessary to include about four times as many patients (at least 30 patients).
Instead of viewing escalation as a process uncoupled from its social context, the present analysis suggests that it is necessary to outline a theory for escalation as a social process in which coordination and cognitive activity are highly interrelated.
In some critically ill preterm infants, escalation of dopamine therapy or addition of epinephrine is necessary yet not always effective indicating the development of pressor resistant hypotension.
Reduction in motion is necessary to create smaller target volumes for dose escalation to improve local control.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com