Sentence examples for escalation based on the from inspiring English sources

We then analyze the reasons why unescalatable locks are generated and propose a new lock escalation method, adaptive lock escalation, which controls lock escalation based on the number of unescalatable locks.

Patient-targeted sedation protocols implement two main features: a structured approach to the assessment of patient pain and distress, coupled with an algorithm that directs drug escalation and de-escalation based on the assessments.

This study demonstrates that intrapatient dose escalation based on toxicity in the preceding cycle dose, as practised in Group B, is feasible.

This study demonstrated that individualised dose escalation based on toxicity in the preceding cycle could be a feasible salvage strategy for treating AGC.

Investigators could stop escalation based on tolerability and/or if the patient had achieved sufficient clinical benefit at a given dose.

The developed survival model may guide intrapatient dose escalation based on dBP and neutropenia and explore the effectiveness of alternate dosing strategies.

Although it remains unclear whether the PCT protocol could not identify the correct patients in whom therapy should have been escalated or whether the intervention was not beneficial per se, therapy escalation based on PCT concentrations cannot yet be recommended in the sepsis setting [ 26].

This allows treatment to the desired dose with escalation based on biologically relevant data, such as hypoxia which was discussed above, that is mechanistically related to therapeutic outcome.

This pre-planned design for combination phase I trials aims to eliminate chances of falsely halting dose escalation, based on a high a priori chance of developing a DLT of one of the drugs (Hamberg et al, 2010b).

In conclusion, our study demonstrated the safety of individualised irinotecan dose escalation based on patient tolerance.

Individualised irinotecan dose escalation based on patient tolerance was not associated with increased toxicity and shows modest activity as salvage chemotherapy for AGC.