Exact(1)
The escalating intake of drugs may have been a vain attempt to elude the emptiness he saw before him.
Similar(59)
In our experience, AN tends to require escalating caloric intake in order to maintain a 1 to 1.5 kg/week weight gain during hospitalization.
In the future, it would therefore be of interest to continue the alcohol intake further into adulthood to see whether the single-housed animals will escalate their intake.
Long access conditions escalated MDMA intake over the 6 h session but not in the first 2 h.
But even when those close loved ones around me started "nagging" me about my escalating weekly unit intake and trying to get me to go to AA meetings, in dingy church halls, I knew I was definitely not an alcoholic.
Rats allowed extended daily access (6 h) to cocaine, consume high doses of the drug and escalate their cocaine intake over days, resembling the pattern of cocaine use seen in human addicts.
Barrett's LSD intake escalated part-way through the album's recording sessions.
However, after a long history of cocaine self-administration, whether or not they escalated their cocaine intake, around 20% of rats continued to seek cocaine, while 80% abstained (Fig. 3).
Rats that were impulsive on a five-choice serial reaction-time task (5CSRTT), which measures a form of motor or 'waiting impulsivity' (HI rats), escalated their cocaine intake in long access sessions to a degree that was much greater than low impulsive (LI) rats or the general population of rats, although they did not acquire cocaine self-administration more readily (Dalley et al., 2007).
Escalated cocaine intake also enhances the propensity of rats to display stereotypies that depend on dorsal striatal DA, and to show changes in dendritic spines, a marker of plasticity, in the dorsal striatum (Ferrario et al., 2005).
Excessive caloric intake is a major driving force behind escalating obesity and type 2 diabetes epidemics worldwide, but diet quality also has independent effects.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com