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The dose was then escalated back to 36 mg m−2 for a further four patients.
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But it's when it comes back, a jolt of lightning, a gasp of air, that the emotions escalate back into my sudden consciousness.
Of the five patients who escalated the dose of iniparib to 8 mg/kg mid-study, one patient de-escalated back down to 5.6 mg/kg due to grade 2 nausea.
If toxicity does not recur, it may be possible to re-escalate back to the full starting daily dose.
When young Thao (Bee Vang), from next door, tries to steal the sacred Gran Torino, Walt becomes enmeshed with the boy's family, first as antagonist and then, gradually, as fierce protector — so fierce that he gets caught up in the neighborhood gang wars, with their escalating back-and-forth of beatings, rapes, and shoot-outs.
When young Thao (Bee Vang), from next door, tries to steal the sacred Gran Torino, Walt becomes enmeshed with the boy's family, first as antagonist and then, gradually, as fierce protector so fierce that he gets caught up in the neighborhood gang wars, with their escalating back-and-forth of beatings, rapes, and shoot-outs.
The film was pilloried upon its world premiere at Cannes in 2003, leading to an escalating back-and-forth between Gallo and Roger Ebert, who deemed the filmmaker's pet project the worst film ever to screen at Cannes.
This use of prostitution escalated when back in his native village, where a Saturday night ritual with a group of friends started.
After Trump escalated a back-and-forth spat with his Republican rival by giving out Graham's personal cell phone number at a campaign rally on Tuesday, the senator released a video in which he destroyed his phone through various dramatic means.
As protests in Northern Africa and the Middle East continue to radiate and escalate, check back here for our coverage and analysis: Libya Jon Lee Anderson writes dispatches from Libya.
By The New Yorker January 28 , 2011As protests in Northern Africa and the Middle East continue to radiate and escalate, check back here for our coverage and analysis: Libya Jon Lee Anderson writes dispatches from Libya.
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