For example, studies in mice have implicated a host of signalling pathways as being critical in proper tooth eruption and development, including those involving the gene families Bmp, Eda, Fgf, Shh and Wnt, among others (3– 5).
A subset of treated embryos further developed for an additional 24 hours under standard conditions (7 dpf; Figure 7a and 7b); the remaining embryos from the same brood were allowed to develop for an additional six days (12 dpf; Figure 7c and 7d) to span the period of both first row eruption and development of the lingual tooth row.
Skin pigmentation, development of the ears, growth of the fur, teeth eruption, and eye development give reliable cues about the age of the pups (±1 day, day of birth was considered as day 1) (König and Lindholm 2012).
A thorough understanding of how the functional variants underlying these associations mediate their effects is likely to yield rich rewards not only in terms of understanding tooth eruption and craniofacial development, but also potentially about how disease develops across the life course.
The majority of current knowledge regarding the genetics of tooth eruption and tooth development has been acquired from studies involving transgenic mice and other model organisms, including fish and reptiles, as well as from clinical genetic studies of humans with congenital disorders in which dental abnormalities are a feature.
"There's been a virtual eruption of research and development activities of all kinds on alternate ways to produce and use energy," he said.
Information concerning infant oral growth and development, including eruption of primary teeth, should be provided.
In our study, investigation of the maxillary first molar was chosen for a number of reasons including its complex root anatomy, early eruption and completion of root development in orthodontic-aged adolescent patients, and its use as an anchorage unit for initial phase orthodontic care.
The development, eruption, and close monitoring of Axial Seamount provided a fertile model on submarine volcanic eruptions to scientists; several scientific papers on the topic were published soon after.
Our results suggest that the genome-wide association approach is a powerful strategy for detecting variants involved in tooth eruption, and potentially craniofacial growth and more generally organ development.
Referring to the character of the eruption and the rapidity of its development, modified smallpox occurs mostly in previously vaccinated people.
