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Because these compounds do not interact with classical ERs, it is also likely that they will not trigger the unwanted side effects of chronic hormone therapy in postmenopausal women, such as increased risk of thrombosis, stroke, cardiovascular events and breast cancer, associated with the activation of classical ERs [3], [4].
Because E2 activates all forms of ERs, it has a composite (positive) profile for inducing cell proliferation.
Although ESS does not contribute strongly to yeast ERs, it is still an important factor in determining bacterial protein evolution.
Due to the standardisation of computable criteria and SQL possible with the ERS, it was also possible to create computable criteria in little time.
This binding site has a different pharmacologic profile than classical ERs: it binds BPA, DES, and E2 at a similar dose.
When performing survival analysis in breast cancer while studying ERs it is important with sufficient follow-up due to the risk of late recurrences.
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Does it go, "Relax, don't do it, when you want to suck it to it"? Er, yes, it does.
The overture needed a decent kickstart, but generally the orchestra mustered sufficient bounce and decorum under David Steadman, and the fine cast includes Nicholas Sharratt's sweet and lyrical Nanki-Poo plus some seasoned G&S-ers: it would be hard not to warm to the exquisite timing and pathos of Richard Suart's hapless executioner.
Er, it's me.
(Er, it doesn't say).
Er, it's nothing, isn't it?
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