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These measurement systems provide real-time analysis that can identify errors and defects on an assembly line.
One of the most important factors that influence the reduction of errors and defects is the number of quality tools and techniques used.
This chapter also covers a number of error-resilient and defect-tolerant designs embedded on-chip to tolerate soft errors and defects.
As is frequently the case in developmental studies, Quirks takes some of its clues on developmental processes and pathways from studies of anatomical errors and defects, but this book offers so much more than just a morbid anatomy of human development.
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The artistic part of reliability measurement lies in the design of the various tests and procedures to stress the system and find out all possible errors, bugs and defects.
Subsequent studies of mice with epiblast-specific deletion of DG resulted in brain and eye malformations that broadly resemble the clinical spectrum of the human disease, including neuronal migration errors, hydrocephalus, and defects in anterior as well as posterior chambers of the eye [ 20].
He goes on to criticise Buffon's description of the crossbill's beak as "an error and defect of Nature, and a useless deformity" as "an erroneous and hasty conclusion".
As the HSA LR model for myotonic dystrophy (DM1) shows similar Clc-1 defects, this study demonstrates that both splice errors and translation defects are required for DM1 pathology to manifest.
Dual depletion of Mbnl1 and Mbnl3 therefore initiates both Clc-1 splice errors and translation defects to synergistically enhance myotonia.
Proofreading would emplace a last line of defense against SNARE assembly errors and consequent defects in cell architecture and function.
As similar defects are observed in the HSA LR DM1 mouse model, where CUGexp aggregate and disable the Mbnl proteins, this study shows that both splice errors and translational defects are required for key features of DM1 pathology to fully manifest.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com