This difficulty in pinpointing reasons for inter-study variation highlights a limitation of the high-throughput experimental methodology employed by ourselves and Wu et al. (2014): while such experiments provide a wealth of data, numerous factors can create noise in these data (sequencing errors, population bottlenecks, epistasis among mutations, etc).
These can be very useful in pinpointing your gap.
There are, however, multiple forms of inaccuracy (missense, premature termination, and frameshifting errors) and pinpointing a particular error process behind apparently adaptive mRNA anatomy is rarely straightforward.
In the interview, Matt commented, "[When I rated without a rubric], I really focused on types of errors, actually pinpointed to detailed error types, for example, incorrect verbs".
The error is likely to have been human, either in not realizing that the convoy contained allies or in mistakenly pinpointing its position as the bull's-eye.
The STOPP criteria allow the detection of potential overtreatment and place a special emphasis on drug disease interactions; the START criteria serve to assist the physician in targeting potential errors of omission by pinpointing treatments that may be indicated but not prescribed [ 21].
In addition, pinpointing the genes driving ecological divergence is a key goal in molecular ecology.
Additionally, PDIviz may be useful in rapidly pinpointing the overall mode of interaction.
Since the algorithm applied by EMMA bases haplogroup assignment on costs (fluctuation rates), high cost profiles may also pinpoint errors in sequence data.
With the rapid expansion of the GenBank database, and the push for compiling and analyzing large amounts of published data from diverse sources, there are fewer chances of replicating experiments that could help pinpoint errors in identification and labeling.
