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It is unclear whether any erroneous transcripts have been issued.
Importantly, in our remapping, Affymetrix probes originally designed from erroneous transcripts are removed.
Accumulation of unprocessed (aberrant) mRNAs can be deleterious for the cell, hence processing fidelity is closely monitored by QC (quality control) mechanisms that identify erroneous transcripts and initiate their selective removal.
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Correction: April 11, 2002, Thursday An article in Business Day yesterday about President Bush's views on the accounting treatment of stock options granted to executives misstated his remarks, based on an erroneous transcript from the White House.
An article in Business Day yesterday about President Bush's views on the accounting treatment of stock options granted to executives misstated his remarks, based on an erroneous transcript from the White House.
Fig. 3C illustrates the potential of our proposed approach also for the identification of potentially erroneous transcript annotations.
The low coverage transcripts (coverage < 10) comprised 16% of transcripts and were likely to include many truncated or erroneous transcript predictions.
NMD is a surveillance mechanism that recognizes and degrades transcripts carrying premature termination codons (PTCs) arising from erroneous transcription or splicing, or that are encoded by splice-site or nonsense/frameshift mutations [ Khajavi et al., 2006].
We then excluded erroneous contig transcripts, which failed our filtering criteria (see Methods).
High sequence divergence may affect binding efficiencies and thus lead to erroneous results regarding transcript abundance.
The pseudomedian filter can result in slightly erroneous identification of transcript boundaries (start and end).
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