Regardless of the method used, erroneous orientation estimate and/or ground model will cause problems as in the erroneous road model case.
Furthermore, erroneous orientation can be the result of poor examination and misdiagnosis.
> To assess the effect of the uneven sequencing coverage and the presence of erroneous orientation in the long-insert libraries, we ran the SSPACE scaffolder on the best assembly (non-amplified Replicate 1) using reads from each long-insert library.
In this analysis of sensitivity, we considered three parameters: (i) the total number of true positive fusions detected by the different tools (called all), (ii) the number of true positive fusions detected by the correct orientation of the two genes (called right), and (iii) the number of true positive fusions detected by erroneous orientation of the two genes (called wrong).
The enhanced resolution has allowed an improvement in overall accuracy and the correction of erroneous side chain orientations found in the original deposition.
We used the difference between the automatic measurement from CADABRA and the corrected estimate as a metric for the number of erroneous flips in orientation.
We measured the number of erroneous flips in body orientation by comparing the output of CADABRA to an estimate of body orientation based on a global optimization from all frames of a fly's trajectory from each movie sequence, part of the error-correcting capacities of the Ctrax software [13].
Using these metrics, we compared the number of erroneous flips in body orientation per second for individual flies and the number of frames with identities swapped per second between pairs of flies.
Measurement of ascending thoracic aorta dimension (double arrows) in an axial plane (a) will yield erroneous values due to oblique orientation relative to the centerline of the aorta, as demonstrated on sagittal (red line, b) and coronal (red line, c) multiplanar reformats (MPRs).
During (pro metaphase, when the CPC becomes concentrated at the inner centromere (Fig. 2), the CPC ensures chromosome bi-orientation by detaching erroneous kinetochore microtubule attachments (a process dubbed "error correction") (Gassmann et al. 2004; Zeitlin et al. 2001a; Hauf et al. 2003; Tanaka et al. 2002).
