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In the early 1950s, US organizations led efforts to eradicate malaria from malaria-endemic countries, although insecticide resistance was beginning to appear and slow the eradication progress (36 ).
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However, during the final stages of the eradication program, progress has slowed down, and a certain degree of variability in the sensitivity of the techniques (including SIT test and IFN-γ assay) has been described at the individual level under Spanish conditions [ 21].
The disease outbreak peaked in late September/early October 2007, and then declined as successful containment and eradication strategies were progressed.
As the Guinea Worm Eradication Program (GWEP) progresses toward its ultimate goal of global eradication, ongoing efforts now focus on the four remaining endemic countries of Chad, Ethiopia, Mali, and South Sudan. 1 This report describes the recent situation in Chad, where an outbreak was detected in 2010 after 10 years in which no cases were reported.
Sustained progress toward eradication will require both improved understanding of infectious reservoirs and efficient development of novel transmission-blocking interventions, such as rapidly acting and highly efficacious therapeutics and vaccines.
Overall, however, the progress towards eradication was disappointing, especially in Africa and in the Indian subcontinent.
With progress toward eradication of poliovirus circulation in most countries of the world, discussions are underway on vaccination policies in the post-eradication era [ 1, 2].
This survey aimed to identify how much these strategies varied between farms, in order to inform assessment of the expected future progress towards eradication of classical scrapie.
The donors commended the tremendous progress toward eradication made in the last year and expressed their desire to help change history and end polio while the opportunity still exists.
The donors commended the tremendous progress toward eradication made in the last year and their desire to help change history and end polio while the opportunity still exists.
However, these three countries have made tremendous progress towards eradication and are recording cases in smaller and smaller areas, indicating that transmission is increasingly confined to certain geographical areas, despite certification-standard surveillance.
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