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Ninety-one participants had equivocal test results and were excluded.
All negative and equivocal test results were considered as IgG seronegative.
A persistent positive infection had no negative or equivocal test results during observation.
Patients with missing, unknown or equivocal test results were excluded from the analysis.
A persistent negative infection had no positive or equivocal test results during observation.
In this study, we increased the specificity of the test by considering those with equivocal test results as non-immune.
Similar(46)
All equivocal tests were re-tested in duplicate, and only graded positive if at least one test was positive.
Positive or equivocal tests were further analysed using the Aptima CT mono-specific platform assay, which has a different target to the Aptima Combo-2.
From the 4 confirmed case-patients who were IgG positive, 2 had equivocal tests for IgM and samples were obtained 36 and 39 days after onset of symptoms; 2 were negative for IgM and samples were obtained 50 and 78 days after onset of symptoms.
Data from health records at obstetric and infectious disease departments were thereby linked to civil registration numbers from women (18 45 years of age) who had positive or equivocal tests at the Statens Serum Institut for antibodies to C. burnetii during 2007 2011.
Cases with an equivocal ISH test result [by chromogenic ISH (CISH) or silver ISH (SISH)] were tested centrally by fluorescence ISH.
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