As a consequence, the effectiveness of cooling in a competitive settings remains equivocal and the recommendations below are limited to prolonged exercise in hot ambient conditions with no or limited air movement.
Exercise is promoted as a quitting aid; however, the evidence for this recommendation is equivocal.
It is difficult to make firm clinical conclusions and recommendations given the equivocal results, the lack of standardized evaluation methods to categorize red blood cell units as G6PD deficient (some of which are questionable), and the limited methodological quality and low quality of evidence.
Current guidelines for the management of irritable bowel syndrome are equivocal or conflicting in their recommendations for the use of these treatments, 11 12324 24 but most of these have been informed by previous systematic reviews, which are potentially methodologically flawed for the reasons discussed, and this has implications for the statements made in them.
But NCVO chief executive Sir Stuart Etherington was more equivocal: "The report makes some sound recommendations for reducing undue bureaucratic burdens on charities, but there are a few 'bad apples' which run counter to the general spirit of maintaining high levels of public trust and confidence in charities.
5 This equivocal evidence has led to disparate recommendations about PSA screening.
Norwegian women are more likely to ignore recommendations to follow-up equivocal and low-grade results compared with those indicating a high-grade lesion (Nygard et al, 2006).
In recent years, Delphi expert panels have frequently been used in a range of medical fields to assist in the development of evidence based recommendations when only limited or equivocal evidence is available [ 20- 22].
The IHC staining intensity was scored as 0, 1+, 2+, or 3+ and categorized as HER2 IHC negative, equivocal, or positive according to the ASCO/CAP guideline recommendations for HER2 testing [ 7].
Similar uses of this methodology have been reported in a range of medical fields to assist in the development of evidence-based recommendations, in the presence of limited or equivocal evidence [ 40, 41].
When accurate interpretation on a tissue block remains problematic despite repeated testing, an equivocal or inconclusive report will be rendered with the recommendation to consider an alternative test such as MSI analysis.
