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Analysts scored the vaccinia-preadsorbed Western blots for the 39-kDa, 124-kDa, and 148-kDa diagnostic bands as present only in the monkeypox lane, absent from the monkeypox lane, present in the monkeypox and vaccinia lanes (i.e., experimental equivocal), or technical equivocal caused by nonspecific background.
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La Forge borrowed a distinction from Suarez and other scholastic philosophers between univocal and equivocal causes.
However, low prevalence of documented comorbid psychopathology in suicides, and concomitant racial-ethnic discrepancies underscore the need for training in death certification, and routinization and standardization of timely psychological autopsies in all cases of suicide, suspected suicide, and other traumatic deaths of equivocal cause.
This diversity might be caused by equivocal evidence on this topic in the period in which most guidelines were developed [ 35].
It indicates that in order to reduce the power loss caused by the equivocal observations, it would be more beneficial to call the equivocal observations with a genotyping error rate 2.5% than 'no-call' with an overall call-rate 97.5% (Fig. 4).
A program called QC-Tradeoff is available online to suggest whether 'no-call' procedure could be conducted to minimize the biases caused by the equivocal observations.
Here, we compare the overall outcome (allele frequency estimation and power of association studies) of these two options and try to offer guidelines for different scenarios to minimize the biases caused by the equivocal observations.
An interesting finding is that the influences of the power caused by the equivocal observations always change monotonically with α from 0 (the model of MCB) to 1(the model of genotyping error).
It indicates in order to minimize the biases caused by the equivocal observations on association studies, the validate procedure is either no-call resulted in MCB or call all of the equivocal observations with genotyping errors, which we had discussed above.
Mitt Romney, for his part, has been equivocal about whether rising temperatures are caused by human action.
Equivocal data are available whether hypothermia, caused by a possible H2S-related fall in energy expenditure and/or due to external cooling measures, assumes importance for organ protection achieved during H2S administration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com