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The available GPCR crystal structures mainly define three different conformations: an "inactive state" in which the receptor is bound to an antagonist or inverse agonist; an "agonist-bound state" but without the G protein, or a G-protein equivalent; and a "fully active state" in which the receptor binds to an agonist and to a G protein or a G-protein equivalent, forming a ternary complex.
While the small AAA domain position varies widely between subunits, all six subunit subunit interfaces are equivalent, forming six rigid-body units within the hexamer (see Figure 3 figure supplement 1 ).
Similar(58)
The implanted equivalents formed mature vaginal epithelium and matrix that were integrated into the mice tissues.
Ker-CT skin equivalents formed a cornified layer by 3 weeks of culture (Fig. 3, bottom left).
ATP is subsequently produced by oxidative phosphorylation, driven by the reducing equivalents formed in the citric acid cycle.
Thiobarbituric acid reactive substances were determined by the absorbance at 535 nm and expressed as malondialdehyde (MDA) equivalents formed.
As they filtered into East Asia, which already had equivalent forms, they were avidly assimilated and multifariously transformed.
(b) Equivalent form.
or, in the equivalent form.
or its equivalent form: (3.1)′.
A. The equivalent form of ( 1.2 ).
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