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Optimization of conventional photoinitiator was shown to lead to a small improvement in template selectivity at equivalent affinity and capacity.
CR6323 also neutralised the same strains as CR6261 but 10 fold variability in subtype neutralizing activity was measured that contrasts with its equivalent affinity for H1, H5 and H9 subtypes (Fig. 5c).
MftR binds two cognate sites in the mftR-mftP intergenic region with equivalent affinity and sensitivity to urate.
However, the fluorescence change in binding the unmodified hASLLys3UUU resulted in an equivalent affinity (Kd ≈ 0.15 ± 0.04 μM).
No sequence preference of Ku and TKu is evident, as indicated by the equivalent affinity for other 36 and 37 bp duplexes (results not shown).
Even though aldosterone is the cognate ligand of the MR, glucocorticoids (GCs) such as cortisol can also bind to this receptor with equivalent affinity [ 6].
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Probe lengths on a single array vary between 50 and 65 nt and are adjusted so that all probes on the array have roughly equivalent affinities for their complementary target DNA molecules.
Mouse and human LSECtin have been shown to bind Ebola virus glycoprotein with equivalent affinities, and the GlcNAcβ1-2Man disacchaside has been demonstrated to be an effective inhibitor of this interaction.
VIP shares 68% homology with pituitary adenylate cyclise-activating polypeptide (PACAP) which is another member of the Secretin family (Campbell and Scanes 1992; Segre and Goldring 1993) and both VPAC1 and VPAC2 bind VIP and PACAP with equivalent affinities (Rawlings and Hezareh 1996).
A quantitative PCR probe and primer set homologous to the ruminant Bov-A2 short interspersed nuclear element (SINE) locus (Mendoza-Romero et al. J. Food Prot. 67:550–554, 2004) demonstrated nearly equivalent affinities for bovine, ovine, and caprine DNA targets, while exhibiting no cross-reactivity with porcine DNA in the quantitative PCR method.
The percentage data were converted into an equivalent binding affinity kA with the following formula (Eq. (6)) derived from the law of mass action.
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