Sentence examples for equatorial cortex of from inspiring English sources

Thus, we wanted to test specifically for the importance of RLC phosphorylation in the localization of myosin II to the equatorial cortex of cells during mitosis, where together with actin and other proteins it forms a cytokinetic ring.

As a control, RLCT20S21-GFP expressing S2 cells showed a significant cytokinesis defect upon Rok depletion (Figure 3A) and also showed a significant failure to localize the myosin to the equatorial cortex of the mitotic cell (Figure 3B, Movie S4).

Further studies should help elucidate the molecular mechanism by which cells differentiate between phospho- and non-phospho-RLC myosin II and specifically recruit the former to the equatorial cortex of a cell in mitosis.

While such a role was suggested by earlier studies showing that Rok is essential for myosin II localization to the equatorial cortex of dividing Drosophila S2 cells [1], this is the first direct demonstration that the RLC phosphorylation state regulates proper recruitment of myosin II to the equatorial cortex.

In gastrula stage embryos, xMELK is no longer present at the equatorial cortex of dividing cells (Le Page et al., 2011).

Collectively, the data in Fig 5 argue that the pathological effects on fibre cell swelling and cataract formation may be a consequence of PKA holoenzyme release from AKAP2 in the equatorial cortex of the lens.

Thus, the widely-held view that myosin II accumulates at the equatorial cortex because of cortical flow is most likely incorrect.

Myosin II recruitment to the equatorial cortex is one of the earliest events in establishment of the cytokinetic contractile ring.

Three furrows were induced: one at the equatorial cortex (now free of mitochondria), and one around each of the relocated, bundled microtubules, cleaving the cell into two daughter cells and two anucleate membrane pockets (Fig. 9, 23 min onward, arrows).

We cannot exclude, however, the possibility that a cytoplasmic pool of Polo could still be recruited to the equatorial cortex even in the absence of the two MAPs necessary for its localization to the central spindle.

Spindle-associated mitochondria (which can be transported along, or anchored to, actin filaments [34]) could serve as a "magnet" for attracting actin subunits or filaments to the vicinity of the equatorial cortex.