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Both of these proteins are assumed to be non-specific; the receptor has equal affinity towards all ligand molecules present in the medium, and equally activates the two effectors, while the intermediary protein acts as a "global" deactivator inhibiting both the receptor and the two effectors with equal strength.
It is currently unclear whether TNF equally activates all three MAPK families in arthritis or has a certain predilection toward activating one of the families in the synovial tissue in vivo.
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46 genes (6%) were only bound by SCL, equally activated or repressed and mainly involved in metabolism (activated genes) and inflammation (repressed genes) (Fig. 6k, l).
These results led us to propose that caspase-8 was equally activated in both cell lines, whereas caspase-3 activation was suppressed in TRAIL-resistant SK-BR-3 cells.
380 genes (49%) co-occupied by SCL/RYBP, but not ETO2, were equally activated and repressed (Fig. 6k, l).
The structures of the vomeronasal projection pathway were equally activated by estrous bedding in C and S male rats.
As TRIM24-AR signature genes are equally activated in TRIM28-high tumors as in SPOP-mutant PCa, TRIM28 expression, easily monitored at mRNA level, could be used to select CRPC patients that might not have SPOP mutation for TRIM24-targeted therapeutics that was previously proposed19.
For instance, in the present study, the left AIPS was equally activated for both hemifields during SO and VS.
Thus, the fusiform gyrus might have been equally activated among the facial conditions because the face scanning strategy showed no difference among conditions in this study.
Upon transfection in HEK293T cells wild type Gadd45a as well as R34G and V49R mutants equally activated the methylated reporter (Figure 5E).
In both SO and VS, a bilateral network of regions with non-spatial functions is activated that does not show a pattern of contralateral preference and should be equally activated by both hemifields.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com