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Although examination of the hydrolysis of pNPA is informative, it is not equal to the native, evolved reaction of CA, CO2 hydration.
A minimum cluster threshold of nine contiguous interpolated voxels (3.49 mm, approximately equal to the native functional voxel volume of 3.31 mm) was also used to further protect against spurious correlations.
The voxel size of the dose point kernel was equal to the native resolution of the image technique (2 × 2 × 6 mm for MRI, 4.7 mm isotropic for SPECT).
As also shown in a previous study [ 6] with the same animal model, osteochondral defects treated with a scaffold alone showed the appearance of a newly formed cartilaginous mantle similar but not equal to the native hyaline cartilage.
In the previous section, experiments on a small protein show that minimization of the HSE energy in high coordination lattices leads to structures with HSE vectors that are very similar (or equal) to the native structure.
Similar(55)
Because there were fewer hits in the shuffled controls than in native sequence, the shuffling process was repeated several times in order to generate several sets of "shuffled hits", in order to have a number of shuffled hits equal to the number of native search window hits.
Cationized BSA (cBSA) was prepared according to the procedure reported by Domen et al. (1987); the number of amino groups was equal to the number of native amino residues of BSA plus the number of carboxylic groups (glutamate and aspartate) which were derivatized with ethylenediamine.
After 106 such randomizations, the associated p-values were estimated by calculating the fraction of times an ICC value that is greater than or equal to the one for the native data set appeared in the distribution of ICCs for randomized sets.
It then recommends synonymous replacement codons having usage frequencies in the heterologous expression host that are less than or equal to the usage frequencies of native codons in the native expression host.
Both the focused-set and random-set compounds were docked, and the top hits were selected using a docking score cutoff value equal to the docking score of the native ligand in each crystal structure.
Otherwise, we set its fitness ω equal to the maximum of either (1 - y new/N 5 or ω native(1 - y native/N), where y new equals the number of gene activity differences between the phenotype s ∞ and s ∞ n e w, and y native equals the number of gene activity differences between s ∞ and s ∞ n a t i v e.
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