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22 The estimated rate of APC new mutations is between 4 and 9×10 mutations/gametes/generation, 23 and equal susceptibility for mutagenesis during spermatogenesis and oogenesis has been described.
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The Daphnia clone used in the experiments is the original host for the parasite and because of high transmissibility and the equal susceptibility of the hosts, prevalence within a homogeneously mixed population can be expected to reach 100%.
For simplicity, all individuals in S are assumed to have an equal susceptibility to infection; age-related susceptibility and prior immune history are not considered.
Figure 6 shows the landslide susceptibility for Mérida State.
No resistance was noted for ceftazidime, meropenem, amoxicillin-clavulanic acid or doxycycline, but 12 (22.2%) isolates had MICs equal to the susceptibility breakpoint for chloramphenicol.
Susceptibilities for fungal isolates were not performed.
In any case, our results suggest that the initial assumption of equal local extinction susceptibility among genera inhabiting the same paleocontinent may account for much of the lower than expected geographic range selectivity [39].
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