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Since most of the treated patients received CLB as the last chemotherapy, the analysis was repeated including only untreated and the 14 CLB-treated patients and equal statistic differences in bfl-1 expression were found as compared to the analysis including all the treated patients (NR vs PR P<0.05 and NR vs untreated P<0.05, data not shown).
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The linearity of the calibration curve of quercetin had a correlation coefficient of 0.995 and a Durbin-Watson (DW) statistic equal to 2.13, and the lack-of-fit test showed P value equal to 0.689 (α = 0.05).
Generally speaking, the q-value averages over the values of the test statistic equal to or greater than Y i.
3) Generate a statistic equal to the sum of the log (p-values) for the genes in the region.
The coefficient for infecting organism had a Wald statistic equal to 3.90 and a p-value of 0.048.
Xie et al. used the McNemar test, which has test statistic equal to to be compared with the standard normal distribution.
A stepwise regression procedure with forward selection and a t statistic equal to 2 were used to define the final model.
Significance levels were then computed by determining the number of times the reference distribution gave a test statistic equal to or greater than the observed value.
To test a null hypothesis H0 : α = β against the alternative hypothesis H1 : α ≠ β, we compute a statistic equal two times the difference of maximum log likelihoods estimated under the null hypothesis and the unconstrained model (13) The distribution of the statistic under the null hypothesis is approximated by the χ distribution with one degree of freedom.
Under the null hypothesis of no association of the set of rare variants with the disease, the average number of rare alleles in cases and controls should be equal and the statistic T G is asymptotically distributed as a central χ (1 ) 2 distribution.
Aside from p-values generated using Fisher's method, the significance of genes shown in Figures 2A and 2B was confirmed by a second method, in which simulation was used to generate null distributions for a test statistic equal to the number of significant results across all tissue types (assuming random association of differential expression patterns among tissues) (P < 0.001 for each gene).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com