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Exact(37)
This gives a simpler expression for the Taylor expansion, A useful expression derived from this is, (A.2) Note that the terms containing (1−2φ) disappear when φ = 1/2 (equal number of cases and controls), meaning that these approximations are particularly good in that case e.g.g
Case control studies were simulated with an equal number of cases and controls (i.e. w = 1/2).
A random subcohort (n = 6,566) was drawn with the intention to obtain an equal number of cases and noncases (n = 5,507).
A follow-up replication study was performed to validate the results of the initial phase with a second cohort of 598 unrelated Han Chinese subjects (Group 2) with equal number of cases and controls.
This process was repeated until the required (equal) number of cases and controls was obtained.
The pooled DNA association studies considered here have equal number of cases and controls N.
Similar(23)
Each dataset consists of an equal number of case (diseased) and control (disease free) subjects.
For observational study the sample size needed to obtain 90% power at a 5% significance level with an equal number of case and controls for the chi-square test on genotypes, is 350 at each group of cases and controls.
The simulations assumed w = 1/2, with equal numbers of cases and controls.
We used balanced samples with equal numbers of cases and controls consisting of 400, 800, and 1600 individuals.
The main disadvantage is that the validity of the comparison depends on equal numbers of cases and controls, as described below.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com