8 It was proven in a head-to-head randomized controlled trial (RCT) that PLD was equal in efficacy and superior in safety profile to topotecan in platinum-resistant patients.
The former include cost and lack of expertise, infrastructure and clinical equipoise (the belief that treatment arms may in fact be equal in efficacy, and if they are not equal, the more efficacious could be either one).
Both compounds were also capable of inhibiting cell invasion with equal efficacy to 1 but with less attendant cytotoxicity.
Overall, agomelatine showed equal efficacy to other antidepressants on all measures, with little likelihood of important differences in efficacy in either direction.
In all clinical trials published to date, including large-scale phase III studies, agomelatine has shown at least equal efficacy to active comparators such as SSRIs and SNRIs.
This analysis assumes that alternative drugs have equal efficacy to prevent CVD events.
While more research needs to be done on the long-term effects re-entry programs have on recidivism reduction, it appears that not all re-entry programs are equal in their efficacy, according to a 2008 examination of re-entry programs by Doris Layton MacKenzie, a professor of criminology at Pennsylvania State University and director of the school's Justice Center for Research.
At the longer duration exposure of 24 hours, the chlorine dioxide and peroxide are roughly equal in sporicidal efficacy.
Benish et al. (2008), however, wish to extend the equal efficacy conclusion to all treatments judged to be bona fide.
The UK's National Institute for Health and Clinical Excellence states that 'they should be treated as equal in terms of efficacy', although the basis for this decision is not clear [ 31].
To be consistent, we increased the first-year efficacy to 90.7% so that the average vaccine efficacy over 2 years would be equal to 87.4%.
