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Both groups have equal baseline characteristics (Table 1).
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We will use the minimisation method for randomisation to assure an equal distribution of baseline characteristics.
The minimisation method will be used for randomisation [ 25] to assure an equal distribution of baseline characteristics to the intervention and control groups.
Because patient response obtained during the disease course is at least of equal importance to baseline characteristics for the aim of the present study, we also performed a Partial Least Squares regression.
In order to assure an equal distribution of baseline characteristics, duos will be randomised with adaptive weights regarding cluster size (one vs. more than one GP), age, sex, high or low percentage of elderly patients in practice (< or > 15%), practice location (rural or urban area) and nurse affiliation (district or practice).
The twelve month time frame also permitted equal ascertainment time of baseline characteristics for those with PTSD and the comparison group.
Baseline characteristics were not equal for both groups (Table 1).
Thus, the model calculates the effect of PTBD compared to EBD only given that the propensity scores (i.e., the observed baseline characteristics) are hold equal.
Moreover randomization will be checked to make clear if baseline characteristics in both groups are equal.
The t test was used to test the null hypothesis that the mean baseline characteristics of the two groups, DSE and ILI, were equal and to test the hypothesis that the 1-year changes for ILI and DSE were equal.
Baseline characteristics will be compared between the intervention arms to see if randomization resulted in equal distribution of characteristics, the purpose of randomization.
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