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Among them, compound 50 was identified as a highly potent and selective FLT3 inhibitor (IC50 = 0.213 nM), which showed equal activities against various mutants of FLT3 including FLT3 (ITD -D835V and FLT3 (ITD -D835V thandis resistant to quizartinib.
Equal activities of three proteins correspond to the triple point, which is a pseudoinvariant point, in the predominance diagram shown in Fig. 3b.
Thus, equal activities in both compartments would give a gradient of 0. A positive or negative difference represents the respective percentage of decreasing of increasing gradient along the studied axis.
The equal activities of the first and second π-π* transition on the phthalocyanine macro-cycle, which can be seen from their equal peak absorption intensity, are achieved by VOPcPhO PC71BM composite nanotubes.
Higher and approximately equal activities were measured for the proximal 220 and 380 bp of the PEG10 promoter.
Hence, a nominal (and relatively very oxidizing) value of Eh for the vacuole was calculated that corresponds to equal activities of Fe+3 and Fe+2.
Similar(49)
Exon 2 grafting created a novel lysozyme with twice the activity of the wild type enzyme, equal activity came from each of the two active sites.
Among the cephalosporins, ceftizoxime was the most active (13% resistance) and importantly exhibited relatively equal activity against both B. fragilis species and non-B.
Unless the subject is engaged in drawing or calculating, equal activity levels don't mean anything.
Compound 17f showed equal activity to Sorafenib against MCF-7 cell line, with the IC50 values of 6.35 ± 0.43 μM.
Though the physical changes that the machine measured were "an index of activity," Shepard wrote, the same results "would be caused by so many different circumstances, anything demanding equal activity (intelligence or emotional)." The same criticism holds true today.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com