Sentence examples for epo part from inspiring English sources

However, the EPO part of the fusion protein does recognize the rat EPO receptor.

Amgen has also sold $26 billion of Aranesp, a longer-lasting form of Epo, though only a small part of that has been for American dialysis patients.

Amgen solved the high-resolution cocrystal structure of erythropoietin (EPO) bound to the extracellular part of the receptor (EPOR) in 1998, which reveals that the EPO EPOR interaction surface is formed by 11 salt bridges, 17 H-bonds, and 2 hydrophobic clusters centered at a pair of crucial phenylalanines (F93).

This is consistent with the hypothesis that the critically ill patient has an anemia that is similar to anemia of chronic disease and is characterized in part by a relative EPO deficiency [ 26].

Figure 6 shows reticulocyte percentage and EPO concentrations for ALT2.

8 12 In part this discrepancy may be explained by differences in EPO dosage, as EPC response to EPO has been shown to be dose-dependent.

Erythropoietin (EPO) stimulates erythropoiesis through its specific receptor (EPO-R).

We suspected that EPO-mediated neuroprotection in EAE might be in part a consequence of an immunomodulating effect on the balance of Treg and Th17 cell populations in either peripheral lymphoid tissue or the central nervous system target organ.

To enable BBB transport, human EPO was re-engineered as an IgG EPO fusion protein, wherein the IgG part is a monoclonal antibody (MAb) against the human insulin receptor (HIR).

It was also apparent that VEGF neutralisation significantly reduced EPO-induced angiogenesis, indicating that this response is mediated, at least in part, by endothelial-derived VEGF.

Similarly, Epo and the Epo receptor (EpoR) play a critical role in neurodevelopment, neuroregulation, and neuroprotection.