Exact(10)
Here we examined how signaling downstream of phosphoinositide 3-kinase (PI3K) regulates different steps of mammary branching using three-dimensional culture models of the mammary epithelial duct.
Loss of functional pendrin expression leads to an enlargement of the membranous labyrinth that displaces mesenchymal cells that normally surround the epithelial duct.
However, the extent or amount of epithelial duct development is decreased in STAT5 knockout animals [ 17].
All four factors were minimally detected in normal breast epithelial duct cells in the healthy individuals of the Benign group (expression incidences ranging between 5.3% and 10.5%).
The female mammary gland is immature at birth and consists of a mainly stromal tissue, with only a rudimentary epithelial duct structure emanating from the nipple.
Immunostaining for pan-keratin revealed that this cell population included epithelial cells which had apparently sloughed into the lumen from the epithelial duct walls (data not shown).
Similar(50)
Telocytes were often observed in the vicinity or even in close proximity with both secretory acini and exocrine epithelial ducts and regulatory nerves and blood vessel apparatuses.
Using high-resolution imaging in two and three dimensions, we demonstrated that postnatal mouse mammary gland lymphatic vessels share an intimate spatial association with epithelial ducts and large blood vessels.
Electron microscopy evidenced the presence of some unmyelinated axons in the interlobular spaces or septa, usually located adjacent to blood vessels and the exocrine epithelial ducts.
This stain combination highlighted the epithelial ducts of the salivary gland (Figure 5A C).
Our results explain why CD44 is always highly expressed in the developing distal tips of epithelial ducts where it binds to hyaluronan in the growing buds [60].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com