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The main objective of episodic therapy is to decrease the duration of the outbreaks [7].
Episodic therapy uses short term, self-administration of the drug during outbreaks.
ADA levels are diminished using maintenance therapy rather than episodic therapy, since prolonged periods in which the drug is sub-dosed are avoided [80].
Therefore, to minimize the risk of adverse effects whenever possible, the medical community decided to recommend using these drugs in short term, or episodic therapy, in mild cases, and long term, or suppressive therapy, in severe cases.
Episodic therapy for HSV-2 has shown less consistent results [12], [13], [14].
One common method for treating recurrent genital herpes outbreaks is 3 5 day episodic therapy with nucleoside analogues.
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Recent trials estimating the effect of episodic HSV therapy on genital HIV-1 shedding, however, have reported little effect [12], [13], [14].
All three drugs are used in both episodic and suppressive therapy.
Although GER-related chronic cough generally has a good outcome, GER is a chronic disease, and cough may return when medications are stopped, so episodic and prolonged GER therapy may be required.
After 2 weeks of intravenous penicillin therapy, recurrent episodic sclerouveitis was observed.
Both paracetamol and non-steroidal anti-inflammatory drugs are effective first-line therapy for episodic tension-type headache [12].
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