Sentence examples for epigenetic environments from inspiring English sources

We examined the genomic features, transcriptional landscape and epigenetic environments of those sites to gain insights into their functional relevance.

Interestingly, we observed that transcription factors prefer specific epigenetic environments (Additional file 3: Figure S6); clusters 1, 2, 3, and 7 were uniquely populated with specific factors such as CTCF and Zzz3.

To suppress alternative lineages, SCL activates expression of select repressors (ETO2 and PRC1 members) and creates a global repressive epigenetic environment, in parallel to activating blood/endothelial-related genes to promote haematopoietic specification.

In this review, we describe how HSFs are able to sense the epigenetic environment, and we review recent data that support their role as sculptors of the chromatin landscape through their complex interplay with chromatin remodelers, histone-modifying enzymes and non-coding RNAs.

Peri-centromeric heterochromatin displays a protein binding profile and epigenetic environment that is clearly different from that of centromeric cores.

These promoter-bound factors in turn recruit co-activator(s), which set up local epigenetic environment that favors the induction by other signals from, e.g., adenosine-containing molecules (Figure 10C).

Increasing evidence demonstrates that ATRA influences the epigenetic environment regulating both DNA demethylation and histone acethylation/deacethylation [ 32– 32].

We propose that the ancestral PAR1 genes share a common epigenetic environment that allows ATRX to control their expression.

This result suggests that the methylation status of this Alu element is under the influence of the epigenetic environment surrounding its insertion site.

In addition, exploration of the epigenetic environment of the APL genome before and after ATRA treatment gave significant insights into PML RAR α chromatin regulation.

To explore how the chromosomal positioning and the consequent epigenetic environment can regulate the firing of replication origins, we relocated different ARS sequences to a common chromosomal position and determined their activation time in S phase.