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Using an individual-based, epidemiological simulation model, gonococcal prevalence was simulated in a heterosexual population of 100,000 individuals after the introduction of vaccines with varied efficacy (10 100%) and duration of protection (2.5 20 years).
To help public health decision makers address these issues, we developed an epidemiological simulation tool for pandemic influenza which enables users to make decisions during a simulated pandemic.
Note that it is not possible to represent concurrency explicitly in the traditional compartmental models used for epidemiological simulation.
In a first phase of a potential outbreak, Switzerland would strictly follow a stamping out policy supported by epidemiological simulation models.
We developed a model which combines: (1) an epidemiological simulation estimating public health benefits in terms of influenza cases and deaths prevented by pediatric vaccination; (2) a cost-effectiveness simulation balancing vaccination costs with savings and improvements in quality-of-life due to disease averted.
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In 2005, the Swiss Tropical and Public Health Institute's 40-strong office computers struggled to run the enormous numbers of epidemiological simulations needed to get "real-world" results.
During this period, the proportion of syphilis cases representing PSS also declined, from being the majority in the twenties, to only 1 9% in 1949 58 [48], [70], [70], in agreement with epidemiological simulations [45].
Alternative epidemiological study designs that use spatially and temporally resolved air quality and exposure models to characterize intraurban gradients were promising based on exploratory epidemiological simulations.
In contrast, exploratory epidemiological simulations suggest that it may be possible to demonstrate the health impacts of PM reductions by predicting intraurban pollution gradients within New Haven using coupled models.
We assessed the feasibility of detecting health improvements in relation to reductions in air pollution for 26 different pollutant health outcome linkages using both sample size and exploratory epidemiological simulations to further inform decision-making needs.
Nevertheless, we conclude that any intervention which affordably suppresses exposure to transmission by proportions similar to that delivered by an ITN to a single user in a population merits consideration for detailed field trials and epidemiological simulations to determine their likely cost effectiveness in the long term [ 69, 70].
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