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These methods require either predefined frequency of oscillations or the assumption of stationarity, which are often invalid in epidemiologic time series.
We developed an online computer application allowing analysis of epidemiologic time series.
Only relatively few studies have examined epidemiologic time trends of biologic subtypes of breast cancer.
We developed a web-based application allowing users to construct periodic regression models for analysis of epidemiologic time series.
The online application allows easy detection of special events in an epidemiologic time series and quantification of excess mortality/morbidity as a change from baseline.
The epidemiologic time series most suitable for analysis are those where the monitored signal consists of a seasonal background with outbreaks.
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Exposure assessment and misclassification of exposure is a well-recognized limitation of epidemiologic time-series studies.
The authors concluded that using one carefully chosen monitoring site is a reasonable approach to characterize exposure of particle number concentrations in epidemiologic time-series studies.
Numerous epidemiologic time-series studies have shown generally consistent associations of cardiovascular hospital admissions and mortality with outdoor air pollution, particularly mass concentrations of particulate matter (PM) ≤2.5 or ≤10 μm in diameter (PM2.5, PM10).
However, high daily temporal correlations of PNCs among monitoring sites have been reported for several European cities (Buzorius et al. 1999; Cyrys et al. 2008; Puustinen et al. 2007), which suggests that using one carefully chosen monitoring site is a reasonable approach to characterize particle number concentrations for epidemiologic time-series studies.
We have presented an online application for analysing epidemiologic surveillance time series.
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