Sentence examples for epc activity from inspiring English sources

Specifically, integrin α5 β1 has been shown to promote VEGF-induced differentiation of EPCs in vitro, highlighting the importance of both structural and cytokine signals in regulating EPC activity following injury.

Functional EPC activity is significantly impaired in case of high inflammatory stimulation, as in heart failure.

However, it is crucial to maintain EPC activity during such in vitro manipulation.

Aberrant EPC activity and the resulting abnormal angiogenesis cause a variety of diseases, such as ischemia, cancer and metastasis.

To identify more pro-angiogenic miRNAs involved in EPC activity, we examined which miRNA(s) may contribute in EPC angiogenesis.

Nitric oxide signaling and reactive oxygen species have also been implicated in EPC activity, potentially affecting their colony-forming potential and ability to counteract ischemic stress [ 26].

In this study we explored protein-coding mRNAs and miRNAs involved in EPC activities.

These findings indicate that targeting miRNAs may constitute a novel strategy for manipulating EPC activities for therapeutic purposes.

Not only hamper late EPC activities in vitro, both microRNAs (especially miR-222) also hindered in vivo vasculogenesis in a zebrafish model.

EPC activities also affect the efficacy of EPC-based transplantation therapy, specifically if only a low number of engraftment migrate to the injured site after infusion, which will limit the clinical applications of EPCs.

The main inputs to our research pipeline were: microarray data from human EPCs, a comprehensive experimentally-validated network of human protein-protein interactions (PPI), human GO annotations, and different sets of research "queries" that represented initial guiding inputs to reduce the search space of potentially novel associations and biomarkers of EPCs activity.