Sentence examples for eoc lines from inspiring English sources

They showed that the expression levels of 35 miRs were significantly different between the EOC lines and IOSE lines.

Our study has made use of a panel of EOC lines with resistance to carboplatin, but we also used a cisplatin-resistant counterpart in parts of the study.

Of these, 31 miRs (88.6%, 31/35) were downregulated in the EOC lines compared with the IOSE lines, including the tumor suppressor miRs, let-7d [ 10], and miR-127 [ 20].

To further explore the relationship between miR-433 expression and p-Rb, we profiled native miR-433 expression by qRT-PCR in the parent A2780 cells and two other epithelial ovarian cancer (EOC) lines, PEO1 and PEO4.

An initial microarray analysis of the human PEO1 human EOC line and novel drug resistant variants revealed low levels of the gene p57 Kip2 as a consequence of carboplatin resistance.

IGFBP7 expression was then investigated in six other independently derived EOC cell lines established as long-term passages from chemotherapy naïve EOC patients [ 19, 46].

The biological effects were evident only in EOC cell lines and not in the non-tumoural ovarian I64-hTERT cell line in spite of the comparable cellular turnover of the two cellular models (Iorio et al, 2005 and present results).

The human EOC cell lines SKOV3, SKOV3ip1, CAOV3, and Hey and the cisplatin-resistant EOC cell line A2780/CP were purchased from American Type Culture Collection (ATCC, Manassas, VA, USA).

To assess the specific biological impact in EOC cells lines, CHKA silencing was performed also on the non-tumoural ovarian cell line I64-hTERT (Iorio et al, 2005).

In the present study, we found that expression of KPNA2 was significantly upregulated in human EOC cell lines and tissues, leading to significant increases in the proliferation and tumorigenicity of EOC cells in vitro and in vivo.

To identify suitable in vitro models for functional analyses, EOC cell lines were screened for SOX11 expression and promoter methylation was assessed in both positive and negative cell lines.