Sentence examples for eoc it from inspiring English sources

Although tumor infiltrating T cells are associated with prolonged progression-free and overall survival in EOC, it remains unclear whether this reflects an active or passive role of T cells.

In an immunohistochemical evaluation by Eltabbakha et al (2004) aiming to investigate the clinical and molecular factors associated with cytoreduction among women with advanced stage epithelial EOC, it was found that p53 expression was a highly significant predictor for cytoreducibility.

In type I EOC, it is reasonable to develop in clinical setting BRAF inhibitors and other MAPK kinase inhibitors in order to improve progression-free survival and overall survival in patients with advanced EOC [ 62], actually treated with conventional chemotherapeutic schedules.

But his would seem to be an argument tailored for a world in which it is assumed that new innovations are to be welcomed unless it can be proved that they pose a serious risk to markets, and I'm not sure that the record of recent financial innovations justifies that kind of an approach.As EOC says, it's not easy to make a strong, serious argument in favour of financial innovation.

Host T-cell responses are associated with favorable outcomes in epithelial ovarian cancer (EOC), but it remains unclear how best to promote these responses in patients.

If this scenario is representative of other EOC patients, it would suggest that many tumor-infiltrating T cells may recognize antigens that are poorly expressed by tumor tissue, possibly due to immune selection during tumor development.

The frequent, selectively high expression of Cyclin A1 in EOC makes it a promising target for T-cell therapies.

Given that uPA and CD44 colocalise with MDR1-positive cells in EOC samples, it could be a useful therapeutic target for therapy in this disease to overcome drug resistance in the late stage of metastatic cancer.

Little is known about the functions of Syndecan-2 in EOC, although it is known to be expressed in both tumor associated stroma and on the surface of epithelial cells [ 34, 35].

Moreover, there could be an unexplored pathophysiological time window for the detection of CA125 in EOC, during which it is expressed on tumor cells prior to being shed into the bloodstream.

The heterogeneity of copy number alterations (CNA) observed in EOC has made it difficult for small studies to be able to accurately identify the true frequency of the less common CNAs or to reproducibly identify CNAs that correlate with clinical parameters.