Sentence examples for enzyme expression changes from inspiring English sources

Interestingly, it was recently reported that suppression of KATP channel activity protects murine pancreatic β cells against oxidative stress through upregulation of antioxidant enzymes superoxide dismutase, glutathione peroxidase and catalase [48], but the mechanism underlying these antioxidant enzyme expression changes was not identified.

Together, these enzyme expression changes point towards a reduction in the pool of available ceramide within the Mwk Purkinje cells.

Empty lentiviral particles generated numerous enzyme expression changes in comparison to uninfected cells, indicating an alteration in antioxidant capacity irrespective of a shRNA target.

An interesting pattern is that, in many cases, P450 enzyme expression changes in long-lived mice and under CR were mirrored by expression differences in females relative to males.

In the present study, the metabolic enzyme expression changes do not indicate that a comparable shift of substrate utilization occurs in our preparations, since the alterations also involve enzymes implicated in fatty acid β-oxidation.

The final subnetwork constitutes a functional module containing significantly altered metabolites and enzymes with expression changes between the active and inactive stage.

Our results suggest that targeted reduction of redox enzyme expression leads to widespread changes in off-target protein expression, changes that are well-insulated between sub-cellular compartments, but compensatory in both the production of and protection against intracellular reactive oxygen species.

Changes in progesterone metabolizing enzyme expression (resulting in enzyme activity changes) may be responsible for promoting breast cancer progression due to increased production of tumor-promoting 5α-pregnanes and decreased production of anti-cancer 20α – and 3α-4-pregnenes.

Changes in progesterone metabolizing enzyme expression (resulting in enzyme activity changes) may be responsible for stimulating breast cancer by increased production of tumor-promoting 5α-pregnanes and decreased production of anti-cancer 20α – and 3α-4-pregnenes.

Next, enzyme expression values and relative changes in the MB treatment situation were estimated according to RT-PCR results (Table 2).

To determine whether the observed modifications of enzyme expression were because of changes in the corresponding mRNA levels, a quantitative real-time PCR analysis was performed.