Sentence examples for enzyme compound from inspiring English sources

The modified enzyme (compound I) catalyzes the production of a free radical (S) and a second modified form of the enzyme (compound II) by an electron transfer from the substrate (SH: reduced substrate): Compound I + SH → Compound II + S.

Against β-glucosidase enzyme, compound 6 g was noted as the lead inhibitor with IC50 value of 0.08 ± 0.002 μM.

Previously, it has been suggested that the oxidation statuses of HRP intermediates and soybean peroxidase intermediates formed in the presence of IAA, namely, [E-IAA] and [E-IAA-O2], may be ferrous enzyme and the O2-bound form of the enzyme (Compound III) in the oxygenase cycle of peroxidases, respectively.

In an in vitro fluorimetric assay using the human GIIA (HPLA2) and porcine pancreatic GIB enzymes, compound 60a (Y = phenoxy, R = C18H37, Z = CH2) had the optimal activity with an IC50 = 30 nM on HPLA2.

For all enzymes, compound 2 was most potent, followed by DD2 and finally compound 3.

In contrast to results with the other enzymes, compound A1 (6′-OH-CB35) was a fairly potent inhibitor of SULT1B1 (Table 3).

Interestingly, like plant enzymes (Compound I), the ferryl intermediates of human hemoglobin oxidize aromatic monoamines (AMAs), leading to the production of AMA radicals and O2-, theough the catalytic cycle so-called pseudo-peroxidase cycle.

Table 3 shows some examples of predicted enzyme-compound pairs with high interaction scores.

For example, Pathview Parser corrects for the improper KEGG definition of enzyme-compound interactions by merging and resolving the conflicting ECrel record and associated reactions records (Supplementary Fig. S2).

This assay showed the highest level of activity at the 5 μM concentrations, indicating a high affinity for this enzyme-compound set, and this activity decreased in a concentration-dependent manner up to 15 μM when the velocity plateaued and remained constant up to 75 μM (the highest concentration assayed).

The classical peroxidase cycle involves the reaction sequence from native enzyme through compound I, then compound II and finally back to native enzyme [ 2].