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This enzyme combines the two middle steps (EC 4.2.1.17 and EC 1.1.1.35) of the β-oxidation cycle.
Since the CAN1 nuclease presented here seems to be associated with PCD and its properties resemble the mycoplasma membrane nucleases, in the future we intend to verify the hypothesis that this enzyme combines DNA degradation with transfer of degradation products between the dying cells and the cells that are responsible for further nucleotide catabolic processes.
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Incubation pretreatment with the function of endogenous enzyme combined with negative-pressure cavitation extraction (IP-NPCE) was established to extract calycosin and formononetin from Radix Astragali.
The important role of this essential enzyme combined with its unique structural features and ubiquitous occurrence in bacteria has made it an attractive new target for the development of new FabH inhibitors.
The important role of this essential enzyme combined with its unique structural features and ubiquitous occurrence in bacteria has made it an attractive new target for the development of antibacterial agents.
Since OPs are more likely to have phenolic leaving groups as compared to electroactive leaving groups, we have developed a new amperometric dual enzyme electrochemical assay that enables the detection of a broad class of OP compounds using the OPH enzyme combined with horseradish peroxidase (HRP).
The current fibrino gen)olytic enzyme combined with its strong fibrino gen)olytic activity revealed the anti-thrombosis mechanism of the traditional medicinal insect, E. sinensi.
This enzyme (combined with enoyl-CoA isomerase) is essential to allow beta-oxidation and consequently energy production for the parasite [ 36].
In the endpoint mode, the assay employed large amounts of enzyme combined with malachite green for the detection of the phosphate.
We recognized that the Oplophorus luciferase offered such an opportunity by the inherent luminescent efficiency of the native enzyme combined with the discovery that the small catalytic subunit was structurally related to iLBPs.
The low basal activity of the enzyme, combined with its inducibility, offers a potential therapeutic approach, and hence the upstream signalling pathways and transcriptional regulation of HO-1 remain a subject of intense interest.
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