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The need of an enzymatic cleaner for soft contact lens care with an improved ocular safety and stability profile led us to evaluate the use of nanoparticles (NPs) of poly(D,L-lactide-coglycolide) (PLGA) and methyl trypsin (MT).
No bacterial contamination after reprocessing was found in 98% of duodenoscopes with Bodedex forte (78 duodenoscopes), in 72% with a conventional cleaner (129 duodenoscopes) and in 69% with an enzymatic cleaner (100 duodenoscopes).
For example, within the fast food industry we wonder whether franchises appreciate the implications of their choice of an enzymatic cleaner on the slip rates.
A 4.5-5.6 log10 reductinn infectivityity of scrapie strain 263 K bioassayed in Syrian hamsters was demonstrated after treatment of contaminated stainless steel wires with vaporized hydrogen peroxide with or without an enzymatic cleaner [ 15].
Similarly, the fast food industry case illustrates how a decision at one level intended to improve conditions (e.g. the choice of a more effective enzymatic cleaner) may have unintended negative impact on control loops at lower levels due to the choice of hot water by staff who are also intending to get maximal cleaning effectiveness.
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A typical solution to this mismatch would be a training intervention directed to recalibrate the workers' expectations (i.e. train them to use cold water with enzymatic cleaners).
Thus, it will often be up to the shift supervisors to monitor whether cold water is used with the enzymatic cleaners.
As noted earlier, the discovery of the problems with enzymatic cleaners was found in a research programme to examine the potential of slip-resistant shoes for reducing slipping accidents.
It is interesting to note that the problem of the enzymatic cleaners was a serendipitous discovery in a research programme that was evaluating COFs relative to the cost/benefits of providing workers with slip-resistant shoes.
However, because of the high turnover rate at the staff level, this training will be a continuing problem, unless the popular assumptions change due to increasing availability and general use of enzymatic cleaners.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com