Sentence examples for enzymatic affinity from inspiring English sources

As previously mentioned, Ste7 on an active scaffold has very high enzymatic affinity for its MAPK targets Fus3 and Kss1 [14], and so we expect a more graded response of MAPK activation in response to Ste7 activation (figure 4 and equation (8)).

The result also suggests that the enzymatic affinity of Trx1 for CD30 has been conserved during mammalian evolution.

Furthermore, PNPLA3 wild type has an ∼12-fold higher enzymatic affinity (Km 4.9 versus 61.1) and a 3-fold lower enzymatic activity (Vmax 14.7 versus 5.4) for the retinyl palmitate as compared with triglycerides (30).

This is a promising approach; however, improvement of the strategy is imaginable by separation of the two parameters r max and K M (maximal enzymatic rate and enzymatic affinity parameter in Michaelis-Menten and derived kinetics).

It may explain why Ray et al. chose the wt.tk as the fusion partner in their second generation TF construct, even though the enzymatic affinity of tTKSR39 mutant to acycloguanisines is higher than that of the wt.TK.

In light of the emergence of resistance against the currently available EGFR inhibitors, our study focuses on tackling this problem through the development of dual EGFR/HER2 inhibitors with improved enzymatic affinities.

The apparent Michaelis Menten constant (KMapp) of the biosensor is calculated to be 1.7 mM, suggesting high enzymatic activity and affinity toward glucose.

Thus, the incorporation of a linker and antifouling molecules is an important interfacial design for both affinity and enzymatic biosensors.

They allow direct observation of molecular interactions in a wide range of affinity and enzymatic assays and act as electron mediators.

Aminoglycoside resistance is mediated by enzymatic modification that diminishes affinity of aminoglycosides for the rRNA A-site [ 65].

When used in antisense constructs, PNA confers chemical and enzymatic stability and high affinity towards complementary DNA and RNA [ 19, 20].